Paracetamol Side Effects: Flu, cold, and fever are some of the most common health issues faced by almost everyone, regardless of the age group. While some conditions can be treated with natural remedies and precautions, some require a medical prescription and effective medicines to cure the disease. Paracetamol is one of the medicines or drugs mainly used to cure seasonal colds and fever. However, a recent study has discovered life-threatening side effects of the drug, leading to organ failure and death.
A recent study from the University of Edinburgh found that paracetamol, a common painkiller used to reduce fever and relieve pain, can cause liver damage. According to recent studies conducted on mice, this common pain reliever harms the liver. The findings shed light on overdosage toxicity, which can sometimes be fatal and is challenging to treat.
The University of Edinburgh conducted research on the effects of paracetamol on liver cells in mouse and human tissue. The results demonstrated that paracetamol can harm the liver in specific situations by interfering with the structural junctions necessary for the healthy operation of nearby liver cells.
Paracetamol is a widely used pain reliever around the world. Most people prefer the medicine because it is affordable, safe, and effective when used as directed. However, drug-induced liver damage continues to be a major clinical issue and a barrier to the development of safer medications. The recent findings emphasize the importance of caution when using paracetamol and may provide insight into how to reduce the harm that can result from inappropriate use. The researchers further aim to study more about how different paracetamol doses and times affect liver toxicity and identify potential targets for new drugs.
The recommended paracetamol dosage varies according to age, weight, and the condition being treated. For adults and children over the age of 12, the typical dosage is 500 mg to 1000 mg every 4 to 6 hours, and should not exceed 4000 mg in 24 hours. To avoid overdosing, the dosages for children are determined by weight and age, with strict prescription to pediatric guidelines. People with liver disease or a history of liver problems, as well as those who drink alcohol frequently, should avoid taking paracetamol. Additionally, pregnant and breastfeeding women should consult with their healthcare provider before taking paracetamol.